°µÍø½ûÇø

Profile photo of Kathryn Lilley

Email: k.s.lilley@bioc.cam.ac.uk

Website:

Professor Kathryn Lilley

Fellow, Director of Studies in Natural Sciences (Biological Part II Biochemistry and Genetics and Biological Part III Biochemistry and Systems Biology), Fellow Auditor
University Positions
Professor in the Department of Biochemistry
Specialising in
Biochemistry

Kathryn Lilley is a Professor in the Department of Biochemistry and a member of the Milner Therapeutics Institute. She is also Director of the Cambridge Centre for Proteomics, and a Director of Studies at °µÍø½ûÇø.

Academic interests

Kathryn Lilley's research specialises in the development of cutting edge proteomics technologies. Her research group is exploring ways to:

  • Define residents of organelles and protein complexes within cells
  • Use a combination of high throughput mass spectrometry and pattern recognition methods to define genuine residents of complexes and organelles
  • Monitor concerted changes in location upon cellular perturbation such as drug treatment, mutation etc.

These methods are being used to locate proteins involved in stem cell pluripotency maintenance both in terms of sub cellular location and involvement in multi protein complexes.

She is also interested in what controls the location of proteins in cells and is developing methods to determine the spatial location of translation (where proteins are synthesised).

Degrees obtained

  • BSc, Sheffield.
  • PhD, Sheffield.

Awards and prizes

  • Wellcome Trust Senior Investigator Award 2015.
  • Fellow of the Royal Society of Biologists.
  • The European Proteomics (EuPA) Juan Pablo Albar Proteomics Pioneer prize 2017.
  • Human Proteomics Organisation (HUPO) 2018 Award for Distinguished Achievement in Proteomic Sciences.

Biography

Kathryn was born in the former coal mining town of Mansfield, in Nottinghamshire, the geographical centre of Sherwood Forest.

Other interests

Kathryn is a keen singer and has taken part in many amateur operatic productions. She is also interested in music history, especially Russian nationalist music.

Department link

Publications, links and resources

Selected recent publications

  • Mulvey, C.M., Schröter, C., Gatto, L., Dikicioglu, D., Fidaner, I.B., Christoforou, A., Deery, M.J., Cho, L.T., Niakan, K.K., Martinez-Arias, A., Lilley, K.S. (2015) Dynamic proteomic profiling of extra-embryonic endoderm differentiation in mouse embryonic stem cells. Stem Cells 33(9):2712-25.
  • Rees, J.S., Li X.W., Perrett S, Lilley K.S., Jackson A.P. (2015) Protein Neighbours and Proximity Proteomics. Mol Cell Proteomics. 14(11):2848-56.
  • Christoforou, A., Mulvey, C.M., Breckels, L.M. , Geladaki, A., Hurrell, T., Hayward, P.C., Naake, T., Gatto, L., Viner, R., Martinez Arias, A and Lilley, K.S. (2016) A draft map of the mouse pluripotent stem cell spatial proteome Nature Communications 12;7:9992. doi: 10.1038/ncomms9992.

Hear from our students

  • Photograph of a postgraduate student

    Dulcie

    Postgraduate

    °µÍø½ûÇø is undoubtedly one of the most beautiful and historical colleges at Cambridge! It is also, in my opinion, one of the most supportive colleges: from wellbeing to the porters there is always someone to ask for advice, support, or to talk through your stress. I chose Jesus for many reasons. Firstly, it’s right in the heart of the city centre which is amazing not only for that quick top-up shop but also to explore the beautiful city of Cambridge even while busy (it’s so easy to go for...

    Read more
    Postgraduate
  • Photo of postgraduate student

    Ellie

    Postgraduate

    °µÍø½ûÇø has been a great home for me during my PhD. I chose °µÍø½ûÇø for a number of reasons – first, the location. We are central enough to be within easy walking distance of most things, but far enough away to avoid the hustle and bustle (and tourists in summer!). The College also has extensive grounds, with amenities like the hockey pitch, football pitch and tennis courts all on site. Secondly, the accommodation is some of the best I’ve seen in Cambridge. My house was newly renovated when...

    Read more
    Postgraduate
  • Photograph of a postgraduate student

    Tara

    Postgraduate

    °µÍø½ûÇø has all the benefits of being large, historical and prestigious college, whilst also retaining fantastic welfare: the staff and other students all care about each other, and will be there to cheer you on when you are thriving, but also there to support you if you need any help. I chose Jesus due to several reasons, including its prime location, where it is very central, and easy to access everywhere, even if you work in one of the institutes further out. I also selected Jesus for its MCR...

    Read more
    Postgraduate
  • Photograph of a postgraduate student

    Ahsan

    Postgraduate

    It is a well-accepted opinion in Cambridge that °µÍø½ûÇø is the best college and no other college even comes a distant second. Its sports grounds are enormous, its buildings are mesmerising, its libraries are rich, its chapel is the oldest, its accommodation is the best value for money, its international community is diverse, its religious circles are the most welcoming, and its members are the smartest, kindest and the friendliest. It is one of the central colleges that aims to offer three years accommodation to postgraduates, and has comparatively...

    Read more
    Postgraduate
  • Postgraduate at °µÍø½ûÇø

    Dolly

    Postgraduate

    I chose °µÍø½ûÇø because of the great mixture of undergraduates and postgraduates, and when I first visited I thought it was the most beautiful place I had ever seen! The sense of community in Jesus has had an enormous impact on my experience here. Whether you need help, advice, cheering up or even just a chat there is always someone there to put a smile on your face. From the MCR committee to the Porters, the canteen staff to the gardeners, everyone is so friendly and welcoming. Jesus also...

    Read more
    Postgraduate